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The first symposium on Charge and Field Effects in Biosystems held in 1983 was created primarily to loosen the bonds of previous conferences by expanding the topics to include not only the electrochemistry of biochemical but also metabolically viable biological systems. In addition, topics were introduced to include the effects of various types of radiation on living entities, electrophysiology, ion and electron transport phenomena, the 'solid state' behavior of biological and artificial membranes, and lastly, the application of bioelectronic techniques to medical, physiological, biochemical and pharmacological studies. The following second and third conferences in 1989 and 1991, expanded further on the topics mentioned above. The 1994 symposium continues the topic expansion to include the effects of electroporation as an approach to cellular modification and genetic mutation.