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The 2nd Annual 2016 International Workshop on Materials Science and Engineering (IWMSE 2016) was held in Guangzhou, Guangdong, China on August 12 - August 14, 2016. The main aim of IWMSE 2016 was to provide a platform for scientists and engineers, to get together to share their research findings, exchange ideas and identify the future directions of R&D in materials science.In this conference, we have received over 272 high-quality papers, however, only 160 articles are included in the proceedings, covering topics such as ceramics and glasses, amorphous materials, nanomaterials and thin layers, soft magnetic materials, biomaterials, polymers, photovoltaic materials, steels, tool materials, composites, as well as functional and smart materials.