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Rational engineering of the methylerythritol 4-phosphate (MEP)


Rational engineering of the methylerythritol 4-phosphate (MEP)

pathway for terpenoid production through metabolic control analysis
1. Aufl.

von: Daniel Volke

CHF 43.00

Verlag: Apprimus-Verlag
Format: PDF
Veröffentl.: 25.07.2018
ISBN/EAN: 9783863596507
Sprache: englisch
Anzahl Seiten: 186

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Beschreibungen

Terpenoids include high value chemicals such as pharmaceuticals, chemical precursors and fine chemicals. Fruthermore, terpenoids are of interest as environmental-friendly replacement of fossil derivate chemicals. Here, the 2 C methyl D erythritol 4 phosphate (MEP) pathway was analyzed in Escherichia coli through metabolic control analysis for production of the model terpenoid isoprene. Several limiting steps were identified and their implication for an efficient pathway design is discussed.

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